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GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner
Lipids were extracted from 2030 mg of frozen liver samples, then 0.180.27 mL of anhydrous ethanol was added (volume ratio 9:1), and the tissue was homogenized at 4C, 2,500 rpm for 10 min
Mechanistically, it acts as a ghrelin mimetic, binding the growth hormone secretagogue receptor (GHS-R1a) the receptor for the endogenous peptide ghrelin, expressed in the pituitary and hypothalamus
- Glutathione purity confirmed to be over 90%
The importance of 3-AR was verified when long-term treatment with AOD9604 in 3-AR knockout mice failed to produce the changes in body weight and increase in lipolysis observed in wild-type control mice
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