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Additionally, obesity and IR both contribute to -cell dysfunction and apoptosis, mechanistically explained by glucotoxicity and increased immunogenicity (the accelerator hypothesis) or by -cell exhaustion due to increased metabolic demand (the overload hypothesis) [23]
Front Immunol (2019) 10:1027
Milk fat globule-EGF factor 8 (MFG-E8) is an antifibrotic glycoprotein in MSC secretomes that strongly inhibits TGF signaling and reduces ECM deposition and liver fibrosis in mice [18]
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Heart health improvement: Integrating L-carnitine into your diet can help improve heart function and reduce the risk of cardiovascular diseases, offering benefits for heart and circulatory system health
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