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However, through several magnetic resonance spectroscopy studies (MRS) it has been shown that GSH levels are significantly decreased in the hippocampus, frontal, and cingulate cortices early in AD progression (Mandal et al., 2022)
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Its sequence comes from a small fragment of a larger protein found in human gastric juice, the digestive fluid produced by the stomach
The consequence is easy to understate: a substantial fraction of the evidence that DSIP exists endogenously and varies with sleep rests on assays that cannot fully distinguish DSIP from related material
The peptide's neuroprotective mechanisms involve activation of the PI3K/AKT signaling pathway, which plays crucial roles in neuronal survival, protein synthesis, and protection against apoptosis
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