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Most obese subjects would harbor inflamed adipose tissue, which could cause a persistent, low-grade, inflammatory response

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J Comp Neurol 373:157172 Lubos E, Loscalzo J, Handy DE (2011) Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities

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Previous measures of tirzepatide activation of human incretin receptors demonstrated increased potency at hGIPR relative to hGLP-1R 16

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