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SMR analysis utilized cis-pQTLs and cis-eQTLs with larger effect sizes and stronger association significance, which meaningfully enhanced statistical power

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Ipamorelins pentapeptide structure features non-natural amino acids including aminoisobutyric acid (Aib) and D-2-naphthylalanine (D-2-Nal), contributing to its selective ghrelin receptor binding properties