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Science 2012;338:949953.ArticlePubMedPMC 115

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But much in the same way that Viagra was originally developed to treat hypertension and its more famous use was discovered during clinical trials, researchers noticed that GLP-1 receptor agonist drugs had a host of other benefits apart from helping diabetic patients with insulin response

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Nearly all veterinary drugs, including NSAIDs, steroids, antibiotics, monthly heartworm preventives, and flea and tick pesticides, undergo hepatic metabolism, meaning the liver must chemically transform them into forms that can be safely excreted

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