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The concentrations ranged from 0.001 to 10 mM for ABTS, from 0.02 to 24 mM for DMP, from 0.2 to 60 mM for guaiacol and from 0.025 to 0.35 mM for sinapic acid

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The molecule was developed by Frank Ng's group at Monash University and Metabolic Pharmaceuticals in Australia during the 1990s and 2000s as a potential anti-obesity drug intended to isolate the lipolytic region of hGH without activating the growth hormone receptor or raising IGF-1.nnIn published preclinical work, the fragment has been shown to stimulate lipolysis, suppress lipogenesis, and modulate the beta-3 adrenergic receptor pathway in adipose tissue rather than acting through the classical hGH receptor

Vitak SA, Torkenczy KA, Rosenkrantz JL, Fields AJ, Christiansen L, Wong MH, et al

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Contexte de recherche connexe WOLVERINE appartient la Recherche sur les peptides de gurison et de rcupration, en associant deux composs complmentaires faisant couramment l'objet de recherches sur les voies de signalisation lies la rponse tissulaire et la rgnration