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A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer

An SF3B1 mutation was recently identified by Bondu et al

J Biol Chem 257(10):57515754 Kopp HP, Kopp CW, Festa A, Krzyzanowska K, Kriwanek S, Minar E, Roka R, Schernthaner G (2003) Impact of weight loss on inflammatory proteins and their association with the insulin resistance syndrome in morbidly obese patients

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Dll4 represents a common pattern among candidates, where the pattern suggests expression was affected due to pathology in the Gdac1129/129 mice