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There was some evidence of asymmetry for MACE (Egger test, P = 0.059), suggesting a potential threat of publication bias

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Tier 3 conditions in detail: Prediabetes The American Diabetes Association defines prediabetes as fasting plasma glucose of 100 to 125 mg/dL, a 2-hour plasma glucose of 140 to 199 mg/dL on an oral glucose tolerance test, or an A1c of 5.7 to 6.4 percent

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