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Moreover, retinal protection was achieved without affecting systemic blood glucose levels in this study, suggesting the protective effects of GLP-1 are independent of blood glucose or insulin [80]

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These data demonstrate region-specific regulation by GLP-1R signaling of 2-AG levels and its metabolism

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doi: 10.1053/j.gastro.2005.04.014 21 TargherGDayCPBonoraE

Approved for short-term treatment of obesity, it works by stimulating the central nervous system to suppress appetite, like how amphetamines affect the brain