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Low protein intake, as in Madras and Soweto, impairs CYP induction: thus, the rate of theophylline clearance in Madras controls was lower than in Manchester controls, but significantly increased in local non-alcoholic patients (44), alongside regular close exposure to kerosene fumes and little ascorbic acid (36, 103)
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That said, most people start to notice results soon after beginning the dosing cycle, which is typically prescribed for between six to 12 weeks
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