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GLP1 receptor agonists promote insulin synthesis through the cAMP PKA pathway, while inhibiting beta cell apoptosis

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Tirzepatide cardiovascular outcome data from the SURPASS-CVOT trial extends these findings to the dual agonist

Outcomes Compared with the SGLT2 inhibitors group, there was no evidence that the GLP-1RAs group was associated with the following outcomes: (1) the new onset of heart failure (HR 0.97

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