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Unlike other NLRP3 modifications, ZDHHC12-mediated palmitoylation modification occurs late in the completion of inflammasome function, which acts as a brake to shut down the inflammasome (76)

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This categorization ignores obesitys classification as a chronic disease by the World Health Organization and Canadian Medical Association

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80 Union CaballeroA.MeronoT.AbergS.NordinE.DicksvedJ.Sanchez-PlaA.et al (2025)