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Ferroptosis was first observed in the kainic acid-induced temporal lobe epileptic rat model (Ye et al., 2019), and was later corroborated in other studies and models of epilepsy (Mao et al., 2019b
In the same study, a significant increase in the G1-phase population following the restoration of miR-199a-3p expression was observed
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This reduction contributes to visible signs of aging, decreased energy, weakened immunity, and increased vulnerability to diseases
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