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Life Sci 253:117694
The deletion of Dnmt1 in excitatory neurons of the dorsal forebrain in mice, although these mice are viable into adulthood, results in hypomethylation, dysregulation of gene expression, defects in dendritic branching, and progressive apoptotic degeneration of dorsal forebrain [74]
Consequently, when Nrf2 signaling is blocked, these indirect bone-protective effects of metformin may be diminished or inconsistent, contributing to the observed variability in trabecular bone outcomes in Nrf2 KO mice
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Abstract Nicotinamide adenine dinucleotide phosphate (NADPH) is an essential electron donor in all organisms, and provides the reducing power for anabolic reactions and redox balance
Li X, Jing G, Guo Z, Guo Z (2025) High-mobility group box 1 in acute kidney injury
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