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Symptoms of severe vitamin B12 deficiency can include visual disturbances, severe joint pain, paresthesia (tingling in the hands and feet), memory problems, depression, anxiety, poor muscle function, ataxia (impaired balance and coordination), changes in reflexes and even infertility

PMID 18347346

If it does not let one participate in activities as one desires, one should see a physician to have a physical exam and objectively determine the amount of gapping present with bilateral valgus stress x-rays

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