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In a mouse model of endotoxemia, LPS rapidly induced S100A8/A9 release and acute cardiac depression, while genetic deficiency of S100A9 or pharmacological blockade of S100A8/A9 with ABR-238901 prevented or reversed myocardial dysfunction and reduced systemic inflammation (Jakobsson et al., 2023)

In addition to Nrf2, activation of PPAR- and the AMPK pathway can also facilitate the GSH system

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Enhanced stability and bioavailability of mulberry anthocyanins through the development of sodium caseinate-konjac glucomannan nanoparticles