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Elevated ROS increases PRDX2 monomer formation, which causes TIMELESS-TIPIN dissociation from the replisome and replication slowdown, thereby inducing replication stress
GSH is present also in the most important cellular districts like mitochondria and nucleus to indicate its central role in several metabolic pathways and protective mechanisms
USA 101 , 1641916424 (2004)
For LCMS analysis, metabolite extracts were analysed by high-resolution mass spectrometry with an Orbitrap Exploris 240 (Thermo) coupled to a Vanquish Flex liquid chromatography system (Thermo)
The Science of the Total Environment 957:177489
PMID: 35563172 mBio 2023 Feb 28;14(1):e0237022
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