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estimated treatment ratio, 1.13
Genotyping results of the mutants are presented in Supplementary Figure S5
If your current treatment is causing symptoms such as nausea, diarrhoea, constipation, or vomiting, and these become difficult to manage in your daily life, it may be worth considering a switch, as you could find the other medication easier to live with
Several reasons may explain slower-than-expected results
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