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The FDA approved Liraglutide, the first generic of a once-daily GLP-1 injection, in December 2024
34 SterneJASavoviJPageMJElbersRGBlencoweNSBoutronIet al
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The following GLP-1RAs showed a significantly higher odds ratio of discontinuation due to adverse events compared with placebo: lixisenatide (odds ratio 2.86 (95% confidence interval 1.48 to 5.51)), semaglutide (2.61 (1.56 to 4.37)), exenatide (2.39 (1.14 to 4.98)), tirzepatide (2.30 (1.30 to 4.09)), and liraglutide (2.15 (1.26 to 3.69)) (fig 8A)
Liraglutide relieves myocardial damage by promoting autophagy via AMPK-mTOR signaling pathway in zucker diabetic fatty rat
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