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& Jin, K
Do not use it if you have a family history of thyroid cancer
Look out for our next Insight about GLP-1 insurance coverage of marketed and compounded products, coming in April
Compounded semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist which may be used for chronic weight management, along with a reduced calorie diet and increased physical activity, for people with an initial body mass index (BMI) of: 30 kg/m^2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)
symptoms include right upper abdominal pain, particularly after eating Hypoglycaemia : More likely if taking Wegovy alongside insulin or sulphonylureas for diabetes [1] [17] Acute kidney injury : Usually related to severe dehydration from vomiting or diarrhoea Diabetic retinopathy complications : Patients with pre-existing diabetic eye disease should be monitored The UK MHRA/EMC SmPC includes a precaution regarding thyroid C-cell tumours observed in animal studies
Here, when the two peptides were administered at a 30-min interval, the plasma concentration of the first peptide returned to baseline upon administration of the second peptide
