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Immunodetection was carried out using primary antibodies: Rat anti-BrdU (BU1/75 (ICR1) (Abcam, Cat#ab6326)) at a dilution of 1:20 in BlockAid Blocking Solution (Invitrogen, Cat#B10710) for CldU detection, and Mouse anti-BrdU (Clone B44) (BD Bioscience, Cat#347580) at a dilution of 1:5 in Blocking Buffer for IdU detection