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References Lin Xi, et al
Cellular Mechanisms of GLP-1 Agonists: Treating Diabetes & Obesity Introduction Synthetic Glucagon-like peptide 1 (GLP-1) receptor agonists (GLP-1 RAs) have revolutionized the treatment of type 2 diabetes and obesity
Liraglutide, brand name Saxenda, which comes in multiple doses and is administered once a day as an injection, Semaglutide, brand name Wegovy, also an injection also but administered weekly
This reduces the risk of hypoglycemia when used alone, though the risk increases when combined with insulin or sulfonylureas
Takeaways for Clinical Practice For high weight loss/glycemic needs: Prioritize GLP-1 RA
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