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Understanding Wegovy and Compounded Semaglutide What is Wegovy

Timing of Dose: It is recommended to administer PT-141 at least 30 to 45 minutes prior to anticipated sexual activity.In female trials, onset of effect was noted around 30-60 minutes after injection, and similarly men report that it takes about half an hour (sometimes up to an hour) to start feeling the effects

doi: 10.3390/jcm10173880 60 ShapiroJCohenNAShalevVUzanAKorenOMaharshakN

While early rodent studies suggested alternating hypothalamic GHRH and somatostatin burst as primary drivers of GH pulsatility, other data implicated somatostatin as the key regulator of secretory timing and amplitude, with tonic GHRH secretion [16,17,18,19]

PMID: 9186261

Obesity yes (PA, BMI 30+ with comorbidity)