Recent Developments: In June 2025, Eli Lilly and Company entered a high-value partnership with Camurus to develop long-acting GLP-1 and dual/triple incretin therapies using Camurus proprietary FluidCrystal technology, with deal terms that could reach up to $870 million
Exendin-4 appears to effectively reverse hepatic steatosis in ob/ob mice by improving insulin sensitivity
Better sleep further amplifies recovery and muscle protein synthesis, creating a compounding benefit
The most common GLP-1 side effects include: Nausea Diarrhea Vomiting Constipation Stomach pain A study from researchers at Mayo Clinic, presented in 2023, found that half of adults taking semaglutide, the active ingredient in Ozempic and Wegovy, experienced side effects, the most reported ones being nausea (38 percent) and diarrhea (9 percent)
Matrix metalloproteinases and their role in mechanisms underlying effects of quercetin on heart function in aged zucker diabetic fatty rats
PMID: 21167196