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Yes, its normal

Korsakova, 108(4), 3848

Predictive factors for intrauterine insemination outcomes: a review

Critical Reviews in Biochemistry and Molecular Biology , vol

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IRE1/XBP1 signaling in tumor growth, angiogenesis, and chemoresistance In parallel to PERK, the IRE1/XBP1 branch of the UPR plays a critical role in sustaining tumor growth and mediating resistance to therapy