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B2 (riboflavin): Riboflavin helps convert food into energy and also acts as an antioxidant

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GLP-1 drugs (like semaglutide) enhance that effect by directly stimulating GLP-1 receptors

Combination rationale: The 1:1 pairing is proposed to act through complementary repair pathways a hypothesis, not a proven synergy

116,117 Although several CT-based scoring systems (e.g., the Balthazar score and CTSI) provide objective, quantitative metrics, radiographic signs of severe lesions often lag behind clinical symptoms

Together, these findings suggest that mitochondrial metabolism can dictate response to 5FU