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Of interest, the down-expression of ACC2 results from an epigenetic process linked to histone deacetylation at the ACACB promoter by Sirtuin 1/6 that are activated by high cytosolic NAD + levels associated with enhanced FAO and reduced glucose metabolism
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Silvagno et al., 2020)
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Results Nestin expressing cells preferentially differentiate into osteoblast lineage cells postnatally Cells expressing Nestin have previously been reported to represent a subset of bone marrow mesenchymal stem cells as they differentiate in vivo into multiple lineages, including osteoblasts, chondrocytes, and adipocytes (27)
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