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The authors compare multiple senolytic strategies including FOXO4-DRI, dasatinib plus quercetin, navitoclax, and fisetin, evaluating mechanisms of action, selectivity profiles, and safety considerations for each approach

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Others dismiss it entirely because large-scale human clinical trials are still lacking

Documentation was thorough and lot numbers traceable

This shift in cellular chemistry is associated in rodent studies with altered substrate utilisation

Tirzepatide is FDA-approved, but this combination is not