Ten of the 12 patients reported complete resolution of symptoms, with the remaining two experiencing an 80% reduction in symptoms
however, its high cost limits its accessibility ( Beyond treatment strategies, significant prevention efforts have been focused heavily on vector control, with long-lasting insecticide-treated nets (LLINs) proving effective in reducing transmission rates in endemic areas ( While visceral leishmaniasis has been the focus of extensive clinical trials, parallel efforts are advancing treatment strategies for cutaneous leishmaniasis (CL), where pentavalent antimonials remain a frontline choice despite concerns around toxicity and variable efficacy across different regions
GSH is incapable of penetrating cell membranes due to its high hydrophilicity and being negatively charged at physiologic pH
Frias J.P., Deenadayalan S., Erichsen L., et al
A typical pattern involves 4 to 6 weeks of daily administration followed by 2 to 4 weeks off
Any additional information required to reanalyze the data reported in this paper is available from the corresponding author upon request