Once GSH is depleted, ROS and reactive nitrogen species escalate, leading to increased oxidative stress, mitochondrial dysfunction, and DNA damage
JAMA: the journal of the American Medical Association
The cost of covering GLP-1s is likely a concern for Medicare plans, too
The choice among the different members of this class depends on our clinical judgement considering the cardiovascular risk assessment, the GIT tolerance, the finance and the compliance of our patient
The distinction matters because true allergies require stopping the peptide while localized histamine responses can be managed
The rodent findings may not directly translate to human risk due to significant species differences in thyroid C-cell biology and GLP-1 receptor expression