The gastric-emptying effect often attenuates over time after dose stabilization
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Duca et al., 2015), thereby improving blood glucose homeostasis and reducing the secretion of lipids by intestinal epithelial cells
329 Lactylation in metabolic disorders Lactylation, as one of the novel PTMs derived from metabolism, interacts with various metabolic pathways and plays an important role in the occurrence and development of metabolic diseases, such as diet-induced obesity, fatty liver disease, including non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), and osteoporosis (Figs
Acknowledgements The authors thank W
[136] Economics [edit] Semaglutide had the highest earnings from sales of medications in the US in 2023, with expenditures of US$38.6 billion