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Let me walk you through the five most common reasons why GLP-1 drugs may not be delivering the weight loss results youre hoping for

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Monitor patients closely for signs of drug interactions and adjust the dosage of concomitant medications as necessary

Patients on semaglutide 1.0mg weekly or tirzepatide 5mg weekly typically see accelerated visceral fat reduction in the first 12 weeks compared to GLP-1 monotherapy

doi: 10.1016/j.cmet.2020.06.008, 50

Instead, schedule a conversation with your PlexusDx clinician to evaluate whether adjustment is appropriate