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Calculating the GSH/GSSG ratio from these measurements provides a reliable indicator of intracellular redox status in preclinical models

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Abstract Background Parkinson's disease is a neurodegenerative disorder characterized pathologically by the loss of nigrostriatal dopamine neurons that project from the substantia nigra in the midbrain to the putamen and caudate nuclei, leading to the clinical features of bradykinesia, rigidity, and rest tremor

G., Tapper, S., & Edden, R

doi: 10.2903/j.efsa.2020.6040 204

Both are required as building blocks for glutathione