B12 is fundamental to a number of important metabolic processes, including: Red blood cell formation Nervous system function Nutrient absorption Adrenal gland support Cognitive function and memory Brain cell regeneration DNA synthesis Mitochondrial metabolism Male and female reproductive health Because of its important role in the nervous system, severe B12 depletion over time can lead to irreversible neurological damage
AOD-9604 does not elevate cortisol levels
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Higgins JPT, Thomas J, Chandler J et al (2021) Cochrane handbook for systematic reviews of interventions version 6.2 Sterne JAC, Savovi J, Page MJ et al (2019) RoB 2: a revised tool for assessing risk of bias in randomized trials
(10) Research has examined how NNMT inhibition affects muscle cell energetics, protein synthesis, and metabolic parameters
Olasupo Odunsi, MD, Medical Director Reviewed July 22, 2026 B12 shots are marketed everywhere as a weight loss booster