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Additionally, not everyone benefits equally from metformin therapy, some experience negative effects as well (DeFronzo and Goodman, 1995) and therefore the microbiome is an important part in the inter-individual variability in drug response
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That doesnt mean its not possible though
The pills are mainly used as boosters
Research indicates that APS helps protect the intestinal barrier, promotes the growth of beneficial gut microbiota, inhibits pathogenic bacterial colonization, and increases levels of SCFAs
However, absorption is the critical factor
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