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doi: 10.1177/1933719116667226 29 HafeziMArabipoorAGhaffariFVesaliSZareeiMHessariZH

Insulin resistance in polycystic ovary syndrome across various tissues: an updated review of pathogenesis, evaluation, and treatment

In addition to preventing protein glycation, PLP is an effective inhibitor of lipid (fat) glycation (Higuchi 2006)

Conclusion: After a comprehensive evaluation of molecular structure, clinical data, IGF-1 signaling, fat-loss efficacy, side-effect profiles, and long-term research utility, the answer is nuanced but clear

However, more extensive clinical trials are necessary to establish long-term effects on glycemic control and complications

In addition, Zhang et al