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Participants were randomly assigned to: 9 mg or 12 mg of retatrutide Or placebo Duration: 68 weeks Lets look at the results

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[1] [2] Receptor Activity in Cell-Based Assays The original receptor pharmacology study measured cAMP production in low-receptor-density clonal cell systems expressing human GIPR, GLP-1R, or GCGR

Earlier readout in non-diabetics showed ~12.4% , at the lower end of expectationsstill clinically meaningful but shy of leading injectables

Also, drinking a lot of water throughout the day to keep the mouth hydrated

A small platform was submerged 1 cm below the water surface, in the center of the northeast quadrant of the tank