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Yu Q, Lu C, Li B, Fang S, Zuo W, Dai F

Certain medical conditions, such as kidney disease or heart issues, may increase the risk of complicationsespecially due to the magnesium content, which in high doses can lead to low blood pressure, flushing, or, in rare cases, irregular heart rhythms

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There are some supplies needed for subcutaneous injection

DeFalco J, Tomishima M, Liu H, Zhao C, Cai X, Marth JD, et al