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When cost is not an issue, the ADA recommends choosing a second-line medication from one of the following: dipeptidyl peptidase-4 inhibitors (DPP4i), glucagon-like peptide-1 receptor agonists (GLP-1-RA), or sodium/glucose co-transporter inhibitors (SGLT2i) [3]

However, it is not all talk and no benefit

[2] Additionally, the Institute for Safe Medication Practices (ISMP) has reported on pen device-related dosing errors that can lead to unintended overdoses

Add an equal volume of vehicle (molecular grade H 2 O), to the remaining samples

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