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Rout S et al

Weight loss is rarely linear, and plateaus of two to four weeks are normal

Enteric Nervous System Modulation BPC-157 directly increased survival of cultured enteric neurons under stress conditions and enhanced proliferation of enteric glial cells (which support neuronal function and participate in gut immune homeostasis)

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Further information can be found in Supplemental Methods

We demonstrate that this effect of a GLP-1R agonist was translationally relevant in human islets through application of a single-cell RNA-Seq (scRNA-Seq) technology, droplet-assisted RNA targeting by single-cell sequencing (DART-Seq) (23), a high-sensitivity scRNA-Seq approach