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Discuss realistic goals, lifestyle modifications, and the importance of dietary and physical activity support alongside medication
This is particularly helpful for patients who have undergone bariatric surgery or lost massive amounts of weight
plans to become pregnant, diabetic retinopathy, multiple endocrine neoplasia type 2
STEP 1 Trial (NEJM 2021) Semaglutide 2.4 mg achieved 14.9% mean body weight reduction vs 2.4% with placebo at 68 weeks
While tirzepatide is currently approved for weight management and type 2 diabetes, the migraine data opens a conversation about potential off-label applications
These energy improvements stem from the consequences of weight loss and metabolic health rather than direct stimulant effects of the medication
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