Seok H, Roo D, Cho S, Song W, Kim JU, Park TH, So KH, Hwang NS (2024) Magnetically assembled endothelial cell-coated spheroid for vascularization
Safety concerns included uncharacterized immunogenicity risks, inadequate impurity and endotoxin testing in available raw material, the unresolved free-base versus acetate salt form distinction, and, for BPC-157 specifically, an angiogenesis mechanism that raises theoretical concerns for patients with undiagnosed tumors
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Clinically, they are used for type 2 diabetes management and sometimes for chronic weight management in eligible adults