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If you were on 0.125 mg, increase to 0.25 mg for 4 weeks, then 0.5 mg, and so on
The American Diabetes Association (ADA) and American Association of Clinical Endocrinologists (AACE) guidelines do not specify unique monitoring requirements for semaglutide beyond standard diabetes care protocols
The key message for microdosing: Semaglutide delivers benefits across doses
Whilst prednisolone and Wegovy do not interact directly at a pharmacological level, several important clinical considerations emerge when these medications are used together, primarily relating to their contrasting metabolic effects
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For refractory OIC in the setting of GLP-1 therapy, peripherally acting mu-opioid receptor antagonists (PAMORAs) like naloxegol (25 mg daily) may be appropriate [6]
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