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This rerouting may appear counterintuitive, but it reflects the unique priorities of erythrocytes, which do not require mitochondria to function but must respond quickly to oxygen fluctuations

doi: 10.1038/srep24838 112 NastasiCCandelaMBonefeldCMGeislerCHansenMKrejsgaardTet al

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Mens Health 41 , 482488 (2023)

Broad Gene-Expression Signal (experimental): Reported studies show changes in gene sets tied to ECM remodeling, antioxidant defenses, inflammatory signaling, and nervous-system pathways