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Dependency for Whitening: The skin whitening effects may fade after discontinuation, leading some users to continually rely on the treatment

It has a pleasant, slightly acidic aftertaste (reminiscent of water with lemon or vitamin C when dissolved in water)

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In September 2025, Lilly quietly terminated one of its two Phase 2 trials for strategic business reasons. 9,10 Scholar Rock (Apitegromab): A selective myostatin inhibitor that only blocks latent myostatin activation, potentially offering a cleaner mechanism