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PloS One 9, e107612
Plasmatic vitamin C reflects the vitamin C intake of a previous day
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The problem is that glutathione levels drop naturally with age, stress, and sun exposure
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The 2024 fusion-peptide work exists precisely because researchers recognized that native DSIPs delivery to the brain is the bottleneck, and engineered around it by fusing DSIP to a blood-brain-barrier-crossing TAT transduction domain (sequence GGGGYGRKKRRQRRR) via flexible GGGGS linkers, expressed and secreted from Pichia pastoris
