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doi:10.3109/03602532.2011.558093
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(More information) Impaired antioxidant protection in selenium-deficient individuals may affect physiological responses to stress
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HFD inhibits the transcription of key antioxidant genes by triggering NRF2 translocation into obese mouse Tregs nucleus, causing a rapid decline in HO-1 expression in Tregs, leading to enhanced oxidative stress and possible ferroptosis, and causing an intensification of obesity and inflammatory responses (156) ( Figure 3 )
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