According to the Summaries of Product Characteristics (SmPCs), nausea is very common with most GLP-1 medications, while abdominal distension, eructation (belching), and flatulence are typically classified as common side effects, though frequencies differ between products
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Type 2 diabetes is an established risk factor for Alzheimer's disease and vascular dementia, with epidemiological studies demonstrating that individuals with diabetes have approximately 1.5 to 2 times the risk of developing dementia compared to those without diabetes
Cells were seeded at a density of 5000 cells per well in 200 l fresh culture medium (DMEM supplemented with 10% fetal bovine serum and 1% penicillin/streptomycin solution) into 96-well flat-bottomed microtitre plates (Costar, Corning, USA) and incubated at 37 C in humidified 5% CO 2 using AutoFlow NU-5510 Direct Heat CO 2 Incubator (NuAire, USA) for 24 hours before treatment
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