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Copper peptide stability, pH compatibility, emulsion type, and ingredient interactions all affect whether the active reaches the skin in a functional form

Pharmaceutics 15:2337 Shen J-J, Xue S-J, Mei Z-H, Li T-T, Li H-F, Zhuang X-F et al (2024) Synthesis, characterization, and efficacy evaluation of a PH-responsive Fe-MOF@ GO composite drug delivery system for the treating colorectal cancer

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A 100mg GHK-Cu vial reconstituted with 5mL of bacteriostatic water produces a concentration of 20mg/mL